http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5278187-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36e8050eec40967e1cbc39ff89f2607d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-22 |
| filingDate | 1991-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1994-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1127efc4802b838d4e7c6ae8557d74c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3380e4e34777724a5a50e77cb8c4bae2 |
| publicationDate | 1994-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5278187-A |
| titleOfInvention | Pharmaceutical compositions |
| abstract | Compounds of formula (II) <IMAGE> (II) wherein R1 and R2 are each separately selected from hydrogen, alkyl, alkenyl and alkynyl groups having up to a maximum of four carbon atoms and being unsubstituted, and alkyl, alkenyl and alkynyl groups having up to a maximum of three carbon atoms and being substituted by one, or in the case of fluoro by one or more, substituents but with the proviso that when R1 is hydrogen then R2 is hydrogen or methyl, or R1 and R2 together constitute an ethylene bridging group, and R3 is a group which under physiological conditions undergoes elimination with the formation of a 3,5-dioxopiperazinyl ring, with the further proviso that the compound is in the meso or erythro configuration when each of R1 and R2 is the same or different unsubstituted or substituted alkyl, alkenyl or alkynyl group, and salts thereof with a physiologically acceptable inorganic or organic acid, are of value as prodrugs, particularly for effecting cardioprotection. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5688797-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5438057-A |
| priorityDate | 1985-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 264.