| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1184db643f65f4e2a9b7858bf079859e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-2525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-107497
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-108331 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5094 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-30 |
| filingDate |
1993-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1993-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9abb8039732ee165f81bc1e7878600a8 |
| publicationDate |
1993-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5262329-A |
| titleOfInvention |
Method for improved multiple species blood analysis |
| abstract |
A lytic reagent composition highly selective in its interactions with the cell membranes of blood cells and also provides a method of using the reagent composition in a semi-automated or an automated system to effect a significantly improved white blood cell differential determination. The lytic reagent composition is characterized by an ability to selectively shrink the white blood cells into the increasing size order of lymphocytes, a midregion consisting mainly of monocytes, other mononuclear cells, some basophils and eosinophils, and neutrophils and can readily be optimized to effect a significantly improved three component separation on the histogram of commercially available semi-automated and automated blood analyzers when compared to the reagents conventionally employed on such instruments. Also provided is a novel blood diluent that exhibits an improved ability to stabilize blood cells without "fixing" the permeability of their membranes, which is critical in the semi-automated analysis or blood cells. This mechanism for membrane stability is particularly effective for maintaining the morphology and size distribution of blood cells for multiple species of animals. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7247484-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6812032-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11358148-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004142318-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5496734-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11441997-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5501982-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9517252-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11541396-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7294307-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5560309-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005169802-A1 |
| priorityDate |
1991-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |