| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ae62e973796fbceddbd650671d2bd20 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2121-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 |
| filingDate |
1992-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1993-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db48e7155af0e89e3638b1e8e28c3355 |
| publicationDate |
1993-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5262175-A |
| titleOfInvention |
Stabilization of radiopharmaceutical compositions |
| abstract |
A method of stabilizing a radiopharmaceutical complex composition is provided comprising the use of an element of Group VII of the Periodic Table selected from technetium, rhenium and manganese, or lanthanum or a transitional metal element or Rare Earth element with Atomic Number of 57 to 71 inclusive that has a range of valency states and an organic complexing compound which is capable of complexing with the radiopharmaceutical element defined above to provide a complex suitable for use in diagnosis and medical treatment, comprising the addition of sufficient of a pharmacologically acceptable weak oxidizing agent to stabilize the radiopharmaceutical complex composition. It is preferred to employ Technetium - 99m as the radiopharmaceutical element, the hemaxmethyl derivative of propyleneamineoxime as the complexing compound and sodium hypochlorite as the weak oxidizing agent. A stabilized composition comprising the same components is also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5811072-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9829139-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02092005-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5686058-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002187099-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1404376-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008260636-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02092005-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8337810-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5919934-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005074402-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5494654-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1404376-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011206606-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009304585-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007269375-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0232294-A2 |
| priorityDate |
1989-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |