| abstract |
Compounds of formula I <IMAGE> wherein X is <IMAGE> or =N-O-, in which R4 is hydrogen or halogen, R1, R2, and R3 independently represent hydrogen or a C1-4 alkyl group, and n has a value of zero to four are disclosed. Also disclosed are pharmaceutically acceptable salts of these compounds, pharmaceutical compositions of these compounds or salts with a pharmaceutically acceptable carrier, the use of these materials as N-methyl-D-aspartate receptor antagonists, processes for preparing these compounds and salts, and methods to treat cerebral diseases by administering an effective amount of these compounds, salts or compositions. |