Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef3e73bf82e05dd388bd59b6da624736 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-363 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-38 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-36 |
filingDate |
1992-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1993-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51605990e60df91e7ecd73682f76277e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1bc934b442e95cd441c34d9f7e8ddcf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b763ed8705f644182602caf52778c479 |
publicationDate |
1993-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5256412-A |
titleOfInvention |
Anti-HIV agent |
abstract |
The invention relates to an anti-HIV agent comprising as an effective component a plasma protein of which the polarity of the amino group of the amino acid residue constituting the plasma protein is chemically modified into a negative moiety by a carboxylic acid, for example, by maleic anhydride or succinic anhydride. Plasma proteins modified with dicarboxylic anhydride, which are the effective components of the anti-HIV agent of this invention, inhibit the formation of large cells in mixed culturing of HIV infected cells and non-infected cells as well as the direct infection of helper T cells with HIV. They are very safe compounds and are expected to be applicable to the treatment of HIV infected patients |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5952009-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9632124-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5629198-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5985275-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9051354-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9734619-A1 |
priorityDate |
1989-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |