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filingDate 1992-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1993-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51605990e60df91e7ecd73682f76277e
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publicationDate 1993-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5256412-A
titleOfInvention Anti-HIV agent
abstract The invention relates to an anti-HIV agent comprising as an effective component a plasma protein of which the polarity of the amino group of the amino acid residue constituting the plasma protein is chemically modified into a negative moiety by a carboxylic acid, for example, by maleic anhydride or succinic anhydride. Plasma proteins modified with dicarboxylic anhydride, which are the effective components of the anti-HIV agent of this invention, inhibit the formation of large cells in mixed culturing of HIV infected cells and non-infected cells as well as the direct infection of helper T cells with HIV. They are very safe compounds and are expected to be applicable to the treatment of HIV infected patients
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priorityDate 1989-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 45.