http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5252721-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be0b97e5d8024b2588a3e4989231ba0b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2123-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2121-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0478 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F13-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-534 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00 |
| filingDate | 1990-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1993-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0e826a488a6f6e5a04fe4a86f3b76e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a523969a4e3cebd2f25c9464ab1e336a |
| publicationDate | 1993-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5252721-A |
| titleOfInvention | S3 N chelating compounds |
| abstract | Novel chelating compounds and the corresponding radionuclide metal chelates are useful for radiolabeling proteins such as antibodies with radionuclide metals such as 99m Tc, 186 Re, and 188 Re. The chelating compounds are of the following formulas: ##STR1## wherein each R is a protecting group; n Q is hydrogen or a protecting group; n each T is independently chosen from hydrogen, lower alkyl groups of from 1 to about 6 carbon atoms, electron withdrawing groups, and lower alkyl groups of from 1 to about 6 carbon atoms substituted with electron withdrawing group(s); n X represents O, S, or NH; n each R' is independently selected from: n --(CH 2 ) n --COOH with n=0 to about 4, n --(CH 2 ) n --Z, wherein Z represents a conjugation group and n is 0 to about 4, n hydrogen, and n a lower alkyl group of from 1 to about 6 carbon atoms; n each R" is independently selected from: n --(CH 2 ) n --COOH, with n=0 to about 4, n hydrogen, and n a lower alkyl group of from 1 to about 6 carbon atoms; and the compound comprises at least one --(CH 2 ) n --Z substituent. n The conjugation group Z reacts with a protein to bind the chelating compound thereto. The radiolabeled proteins have diagnostic or therapeutic use, depending on the radionuclide metal chosen. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0724601-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0724601-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9520603-A1 |
| priorityDate | 1990-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 256.