http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5252597-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a717ea5b2ac78ac329ab3a9659d834d2 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
filingDate | 1992-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1993-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61d6a55d1c9f92abb97a45472481cc09 |
publicationDate | 1993-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-5252597-A |
titleOfInvention | Antihypertensive benzopyran derivatives |
abstract | Disclosed herein are novel benzopyrans represented by formula (I) ##STR1## wherein R 1 is trifluoromethoxy or β,β,β-trifluoroethoxy; R 2 , and R 3 are independently selected from the group consisting of hydrogen, lower alkyl containing 1 to 5 carbon atoms, cyclo lower alkyl containing 5 to 8 carbon atoms, ##STR2## or R 2 and R 3 are joined to form (--CH 2 --) n wherein n is 4 to 7; or R 2 and R 3 are joined together to form (--CH 2 --) m CO-- wherein m is 3 to 6; or R 2 and R 3 are joined together to form ##STR3## wherein R 4 is selected from the group consisting of hydrogen, alkoxy containing 1 to 5 carbon atoms, amino or mono- or disubstituted alkyl amino wherein said alkyl groups contain 1 to 5 carbon atoms and the pharmaceutically acceptable salts and solvates thereof, to a process for preparing them, to pharmaceutical compositions containing them, and to their use in the treatment of hypertension, asthma, imitable bladder syndrome, and irritable bowel syndrome. |
priorityDate | 1990-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 137.