| abstract |
PCT No. PCT/JP91/00578 Sec. 371 Date Mar. 9, 1992 Sec. 102(e) Date Mar. 9, 1992 PCT Filed Apr. 26, 1991 PCT Pub. No. WO91/11752 PCT Pub. Date Nov. 28, 1991.1. An estradiol percutaneous administration preparation comprising: (1) a (A-B) nX or (A-B) n-A type elastomer wherein A is substantially monovinyl-substituted aromatic compound polymer block, B is substantially a conjugated diolefin copolymer block, n is an integer of 3-7, and X is a residue derived from a polyfunctional compound combined with n of polymer chain (A-B), (2) crotamiton and (3) a super absorbent polymer, the preparation further comprising estradiol as the medicinal ingredient and exhibiting sufficient medicinal efficacy without causing rubefaction, rashes and the like. |