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filingDate 1991-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1993-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8078ca26f09682c562dd02c1a15d978
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publicationDate 1993-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5229284-A
titleOfInvention Enzyme immobilzation on a macropermable agglomerate of microporous α-a
abstract Enzymes are immboilized on an inorganic carrier which is a round, macropermeable agglomerate having a mulberry-type structure formed from spherical microporous alpha -aluminum oxide hydroxide particles. An organic polycondensate having free organic functional groups as enzyme binding sites penetrates the agglomerate. The alpha -aluminum oxide hydroxide particles of the agglomerate retain essentially their form prior to agglomeration. The polycondensate is prepared by reacting a polyimine with a dialdehyde or an epoxy compound. Preferably, the polyimine is polyethyleneimine, the dialdehyde is glutardialdehyde and the epoxy compound is an epoxy-functional silicon resin, an aliphatic diepoxide or an aliphatic triepoxide. The agglomerate is prepared by granulating the alpha -aluminum oxide hydroxide particles in the presence of the polyimine to form the agglomerate having the polyimine dispersed throughout and then reacting the polyimine with the dialdehyde or the epoxy compound. A preferred enzyme is glucose isomerase.
priorityDate 1990-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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