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filingDate 1992-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1993-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1993-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5219743-A
titleOfInvention Method for optical resolution of corey lactone diols
abstract The primary hydroxy group of Corey lactone diols is optically selectively acylated to obtain the desired optically active ester and/or diol. The mixture of Corey lactone diols of formulae (Ia) and (Ib): ##STR1## is reacted with an acylating agent optically selectively in the presence of an enzyme and/or a microorganism thereby to acylate, isolate and purify the primary alcohol.
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