http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5214070-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d78cd2835221849f6a74e6349185819 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c8bffd30b513a7c8ac7d736fa3ef27f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-18 |
| filingDate | 1991-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1993-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_369e640328c26b6c0a7ae34929abab54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d239bf042905bfd3ba9c19af3fcc1ff |
| publicationDate | 1993-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5214070-A |
| titleOfInvention | Diaryl ether cycloalkanes |
| abstract | The invention concerns a diaryl ether cycloalkane of the formula I, or a pharmaceutically-acceptable salt thereof, <IMAGE> I wherein Ar1 is optionally substituted phenyl or naphthyl; X1 is oxy, thio, sulphinyl or sulphonyl; Ar2 is optionally substituted phenylene, or a 6-membered heterocyclene moiety containing up to three nitrogen atoms; R1 is (1-6C)alkyl, (3-6C)alkenyl, (3-6C)alkynyl, cyano-(1-4C)alkyl or (2-4C)alkanoyl, or optionally substituted benzoyl; and R2 and R3 together form a (3-6C)alkylene group which defines an optionally substituted ring having 4 to 7 ring atoms. The invention also concerns processes for the manufacture of a diaryl ether cycloalkane of the formula I, or a pharmaceutically-acceptable salt thereof, and pharmaceutical compositions containing said cycloalkane. The compounds of the invention are inhibitors of the enzyme 5-lipoxygenase. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5334614-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5420298-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5457125-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5407945-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5376680-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5367079-A |
| priorityDate | 1989-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 271.