| abstract |
Compounds for the treatment of cardiac insufficiency, an arterial thrombo embolism, an arterial occlusive disease, psoriasis, neurodermatitis, asthma, platelet aggregation and hypertension, of the formula ##STR1## in which R 1 is hydrogen, C 1-6 -alkyl, C 2-6 -alkenyl or C 3-7 -cycloalkyl, n R 2 is hydrogen, C 1-6 -alkyl, C 2-6 -alkenyl or C 1-6 -hydroxyalkyl, n R 1 and R 2 together with the carbon atom which carries them can be C 3-7 -spiroalkyl, n R 3 is hydrogen or C 1-6 -alkyl, and n R 4 is a cyanamido group, a 4-difluoromethoxy-3-pyridyl group or a C 1-2 -nitroalkyl group, and n Z is oxygen or sulphur, n or a salt, acid addition salt, tautomer or optical isomer thereof. |