| abstract |
The invention provides antifungal agents of the formula: ##STR1## and their pharmaceutically acceptable salts, wherein R is phenyl optionally substituted by 1 to 3 substituents each independently selected from halo and CF 3 ; n R 1 is C 1 -C 4 alkyl; n R 2 is H or C 1 -C 4 alkyl; and n "Het", which is attached to the adjacent carbon atom by a ring carbon atom, is selected from pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl and triazinyl, "Het" being optionally substituted by C 1 -C 4 alkyl, C 1 -C 4 alkoxy, halo, CF 3 , CN, NO 2 , NH 2 , --NH(C 1 -C 4 alkanoyl) or --NHCO 2 (C 1 -C 4 alkyl). |