http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5196429-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12ebbccf13fdf78bd50c9633c103d352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_363be75f3ed38df3ffca1c3c4092c430 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 |
filingDate | 1991-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1993-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4810f9b8bb3d95c11c16a264c387975d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98ffa02c5a6670c92a67040a8cc1e307 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cba0ca86d2765e50375cad562550eefd |
publicationDate | 1993-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-5196429-A |
titleOfInvention | Method of inhibiting the activity of leukocyte derived cytokines |
abstract | A family of compounds effective in inhibiting interleukin-1 (IL-1) activity, tumor necrosis factor (TNF) activity, and the activity of other leukocyte derived cytokines is comprised of 7-(oxoalkyl) 1,3-dialkyl xanthines of the formula <IMAGE> (I) in which R1 and R2 are the same or different and are selected from the group consisting of straight-chain or branched alkyl radicals with 2 to 6 carbon atoms, cyclohexyl, alkoxyalkyl and hydroxyalkyl radicals, and A represents a hydrocarbon radical with up to 4 carbon atoms which can be substituted by a methyl group. Another family of effective compounds is identified as <IMAGE> (II) The inhibition of IL-1, TNF, and other cytokines in mammals is implicated in alleviation of a wide variety of disease conditions. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6197207-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9605836-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5565462-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9427985-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9605836-A3 |
priorityDate | 1986-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 136.