http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5196419-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d78cd2835221849f6a74e6349185819 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c8bffd30b513a7c8ac7d736fa3ef27f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 |
filingDate | 1991-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1993-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11916cbdac6e77cbb054a00899ad792b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03da285df2dc7c0b3ad7146774cb979b |
publicationDate | 1993-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-5196419-A |
titleOfInvention | Heterocyclic cyclic ethers |
abstract | The invention concerns a heterocyclic cyclic ether of the formula I <IMAGE> I wherein Q is an optionally substituted 6-membered monocyclic or 10-membered bicyclic heterocyclic moiety containing one or two nitrogen atoms; A is (1-6C)alkylene, (3-6C)alkenylene, (3-6C)alkynylene or cyclo(3-6C)alkylene; X is oxy, thio, sulphinyl, sulphonyl or imino; Ar is phenylene which may optionally bear one or two substituents or Ar is an optionally substituted 6-membered heterocyclene moiety containing up to three nitrogen atoms; R1 and R2 together form a group of the formula -A2-X2-A3- which, together with the oxygen atom to which A2 is attached and with the carbon atom to which A3 is attached, defines a ring having 5 to 7 ring atoms, wherein A2 and A3 each is (1-3C)alkylene and X2 is oxy, thio, sulphinyl, sulphonyl or imino, and which ring may bear one, two or three substituents; and R3 is hydrogen, (1-6C)alkyl, (2-6C)alkenyl, (2-6C)alkynyl or substituted (1-4C)alkyl; or a pharmaceutically-acceptable salt thereof. The compounds of the invention are inhibitors of the enzyme 5-lipoxygenase. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-1081645-C http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5334614-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5478843-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5367079-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5376680-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5407945-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5420298-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5457125-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5665749-A |
priorityDate | 1989-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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