| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d037bc74e34c7d73dd883f208aef0518 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-14 |
| filingDate |
1992-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1993-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d709ff64280e8b36137ddd0856cafac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_777470b93755dcfd66dc9dddd4b708db |
| publicationDate |
1993-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5194424-A |
| titleOfInvention |
C63 -amide derivatives of 34-de(acetylglucosaminyl)-34-deoxy-teicoplanin and their use as medicaments against bacteria resistant to glycopeptide antibiotics |
| abstract |
C63-Amide derivatives of 34-de(acetylglucosaminyl)-34-deoxy-teicoplanin wherein the amide moiety is derived from a di- or poly-amine. The derivatives are prepared by reacting 34-de(acetylglucosaminyl)- 34-deoxy-teicoplanins with an active esters forming reagent such as chloroacetonitrile and then contacting the resulting active esters with the appropriate di- or poly-amine. The amide derivatives which are active against Gram-positive microorganisms, in particular against Group A Streptococci were found to be active also against bacteria which are resistant to glycopeptide antibiotics. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5939523-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5843679-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5869449-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6699836-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5977062-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6218505-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5840684-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5843889-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5919756-A |
| priorityDate |
1988-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |