abstract |
Pretreatment of eliminating stratum corneum form the skin for non-invasive measurement of biomedical substances in blood has been improved as to time required, pain to man for test, stability of extraction and invasion to the skin, by introducing chemical and/or steam-spraying treatment(s) of the skin to swell and/or decompose keratinized cells and/or an adhesive strength detector to monitor the elimination level. |