| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5128cfc84a0fb189fceb3cd240c44493 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-00 |
| filingDate |
1991-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1993-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6064f618c89653decccdd29a3bd9add8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76ea88a40cc40284375daacd92ea1656
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_249ed4be1bee2f788a284cf0e61dee00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ad90146501893d02536fcf3f5670541
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0b804f7d49d69bb3cb18fdc30cccc58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_739e8eb261f7e9011a1bc7c37c633a27 |
| publicationDate |
1993-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5187174-A |
| titleOfInvention |
6'-deoxy-6'-halo-neplanocin A and its production |
| abstract |
A compound of the formula <IMAGE> wherein A is adenine-9-yl and X is halogen, Preferably iodine, or a pharmaceutically acceptable salt thereof. It is a novel derivative of neplanocin A and has almost the same level of cytotoxic activity. However, it is not inactivated by the action of adenosine deaminase. It is produced by replacing a hydroxyl at position-6' in neplanocin A or 2', 3'-O-protected neplanocin A with halogen by use of a halogenating agent, and when hydroxyl at position-2' or -3' is protected, removing the protective group thereof. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009270431-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007047793-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007047793-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5605903-A |
| priorityDate |
1989-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |