http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5179118-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a717ea5b2ac78ac329ab3a9659d834d2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-415 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 |
| filingDate | 1992-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1993-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73a5ab2d6cff0d4b678a06d6f1b9aa56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5825f3800f9d80f7f381aa734c65a9f6 |
| publicationDate | 1993-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5179118-A |
| titleOfInvention | Indazolanonyl derivatives of benzopyrans |
| abstract | The compounds of the formula: <IMAGE> wherein R1 is C1-6 perfluoroalkoxy, C1-6 perfluoroalkyl, C1-6alkyl, C1-6 alkoxy, hydroxyl, C2-6 alkoxycarbonyl, nitro, cyano, halogeno, C1-6 alkylsulfonamindo, C1-6 perfluoroalkylsulfonamido, amino, C2-6 alkanoylamino, C2-6 perfluoroalkanoylamino, C1-12 mono- or di-alkylamino, C1-6 alkylsulfonyl, C6-12 arylsulfonyl, carboxyl, or C2-12 mono- or di-alkylcarbamoyl; R2 is hydrogen, C1-6 perfluoroalkoxy, C1-6 perfluoroalkyl, C1-6 alkyl, C1-6 alkoxy, hydroxyl, C2-6 alkoxycarbonyl, nitro, cyano, halogeno, C1-6 alkylsulfonamido, C1-6 perfluoroalkylsulfonamido, amino, C2-6 alkanoylamino, C2-6 perfluoroalkanoylamino, C1-12 mono- or di-alkylamino, C1-6 alkylsulfonyl, C1-12 arylsulfonyl, carboxyl, or C2-12 mono- or di-alkylcarboamoyl; R3 and R4, independent from each other, are C1-6 alkyl; either R5 is hydrogen, hydroxyl, C2-6 alkanoyloxy, C7-12 aroyloxy, carbamoyloxy, formyloxy, C2-6 alkoxycarbonyloxy, mono- or di- C2-12 alkylcarbamoyloxy, and R6 is hydrogen, or R5 R6 together are a bond; R7 and R8, independent from each other, are selected from the following: C1-6 perfluoroalkoxy, C1-6 perfluoroalkyl, C1-6 alkyl, C1-6 alkoxy, hydroxyl, C2-6 alkoxycarbonyl, nitro, cyano, halogeno, C1-6 alkylsulfonamido, C1-6 perfluoroalkylsulfonamido, amino, C1-6 alkanoylamino, C2-6 perfluoroalkanoylamino, C1-12 mono- or di-alkylamino, C1-6 alkylsulfonyl, C6-12 arylsulfonyl, carboxyl, C2-12 mono- or di-alkylcarbamoyl, or hydrogen; and R9 is hydrogen, C1-6 alkyl, C2-6 alkylcarbonyl or C2-6 alkylsulfonyl; or a pharmaceutically acceptable salt thereof are useful as smooth muscle relaxants, as antihypertensives and K channel activators. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9323393-A1 |
| priorityDate | 1992-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 157.