| abstract |
An isocarbacyclin derivative represented by the following formula [VII'] <IMAGE> wherein A represents, a hydrocarbylcarboxylate group, a carboxymethoxycarbonyl group, an amide group, an acyloxymethyl group or a hydroxymethyl group; R4 represents H, a methyl group or a vinyl group; R5 represents a (substituted)alkyl group, a phenyl group, a phenoxy group or a cycloalkyl group; Re22 and Re32 represent H or a hydroxyprotecting group; n is 0 or 1; and a pharmaceutically acceptable salt thereof. |