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filingDate 1990-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1992-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_535da8f10dfc9097554744a213978d5e
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publicationDate 1992-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5165924-A
titleOfInvention Serum-free, cell-free vaccine effective against pneumonic pasteurellosis in cattle
abstract A serum-free vaccine effective against pneumonic pasteurellosis in cattle comprising a non-toxic leukotoxin specific for ruminant leukocytes is disclosed. The leukotoxin is prepared in a serum-free medium from a culture of Pasteurella haemolytica. The produced leukotoxin is harvested from the culture medium upon detecting a certain stage during the logarithmic phase of the cell growth to obtain the optimum concentration of produced cytotoxin in the serum-free medium. Cattle may be treated with the vaccine to develop anti-leukotoxic immunity to pneumonic pasterellosis.
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0694560-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5336491-A
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0810283-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0694560-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6770275-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6037321-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0810283-A3
priorityDate 1986-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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