| abstract |
A process is described for the preparation of compounds of the formula <IMAGE> in which W is C1-7 alkylene X is cis or trans -CH=CH- or -CH2Ch2- Y is a saturated heterocyclic amino group, and R2 is substituted or unsubstituted phenyl-, thienyl- or naphthyl-alkyl, or cinnamyl, and their salts and solvates. The process comprises hydrolysing a corresponding ester, amide, nitrile or ortho-ester. The starting materials are preferably prepared by reducing the corresponding cyclopentanone and hydrolysis can take place simultaneously with reduction. |