| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14ff083cfde502b99517c488b8e38df6 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-832 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-099 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
| filingDate |
1989-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1992-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddbcc2d6769c556143ee84d8c446f728
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_730fc997cce922e314de19278a99cdbf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcf2bb2e0a421987a781c2ca44e2b5d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15c44d14921d8ee4680f5114a4622d6a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f780fd76b1f08d71aa50e99df190faf |
| publicationDate |
1992-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5139776-A |
| titleOfInvention |
Method for culturing Bordetella pertussis, a pertussis toxoid and a pertussis vaccine |
| abstract |
There is disclosed a method for culturing Bordetella pertussis in the presence of a cellulose and/or cellulose derivatives. The present method is useful for obtaining a mixed antigen comprising pertussis toxin and filamentous hemagglutinin in a large amount at low cost. From the antigen, there can be obtained a stable and effective pertussis toxoid to be used for a pertussis vaccine. There is also disclosed a vaccine comprising the pertussis toxoid as an active ingredient and a gelatin and/or gelatin derivatives as a stabilizing agent. The present vaccine is extremely stable and can be stored for a prolonged period of time. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7077044-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6638739-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6432411-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7240618-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5332583-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113151081-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6120627-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6644200-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6660112-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6668725-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005026866-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004250674-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6420139-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004260141-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03016226-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7008790-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007237782-A1 |
| priorityDate |
1987-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |