abstract |
Reaction schemes for carrying out a variety of chemical synthesis are disclosed. The reactions produce α-(X)-sialosides wherein X is O, S, N or another compatible electron donating atom or molecular moiety. The reaction schemes include a relatively small number of steps to provide a yield with a relatively small amount of undesired β-configuration product. Compounds synthesized are encompassed by the following general structural formula I. ##STR1## wherein R, R' and R" are each independently H, CH 3 , acetyl, or a disaccharide which is preferably lactose. |