| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09fc02a407043ca0a10e2dbe5fcb6159 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-948 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-743 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74 |
| filingDate |
1989-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1992-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34f61faedf8b0b11dba2b7f17442ba95
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f744c862ab405fdce85d5e1d3d85cc1b |
| publicationDate |
1992-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5135849-A |
| titleOfInvention |
In-vitro methods for identifying compositions which are agonists and antagonists of androgens |
| abstract |
The present invention provides general protocols by which a substance may be identified and characterized as an androgen agonist and/or an androgen antagonist. The described protocols are in-vitro methods which utilize androgen dependent cells in culture and a medium comprising an inhibitor endogenous to the sera of humans and animals which is able to prevent the proliferation of these cultured cells in-vitro. The methodology is rapid, reproducible, and accurate; and provides the major advantage of being able to test large numbers of unevaluated substances for their androgen agonistic and/or antagonistic properties as primary properties or secondary side-effects. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2394659-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2394660-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8563249-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010278729-A9
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6274305-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03059283-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7425565-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6165504-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03059283-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6645954-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010303825-A9
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003153627-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002012954-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2359857-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004132776-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6768026-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008226549-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8038999-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003072760-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011086800-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7947275-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8119138-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6613758-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7947463-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0185210-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9728250-A1 |
| priorityDate |
1986-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |