| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec5b8c0fc1f827c1360a8f5ea5652225 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2219-15 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M21-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-00 |
| filingDate |
1991-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1992-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd140ec109dc7f42821f0cc365dd97d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cb66570abc3ccc8b2d68d13515736a3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a6159c70f98043dc1b4fcfe08958b33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65af90bde9c018bda5005bf95c6c06a3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0b2302ed2516aef4064981855e35d2e |
| publicationDate |
1992-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5122462-A |
| titleOfInvention |
Process for the enzymatic preparation of optically-active cyanohydrins |
| abstract |
The preparation of optically-active cyanohydrins from the corresponding oxo compounds is disclosed. The reaction of the oxo compounds with hydrocyanic acid is carried out in an organic solvent in the presence of (R)- or (S)-oxynitrilase (4.1.2.10) and (4.1.2.11), respectively, being solubilized in a lyotropic liquid crystal. Compounds which upon hydrolysis produce increased pH values are excluded as surface active agents. Preferably, surface active agents, the organic solvent and an aqueous buffer solution with a pH of 3 to 6, are mixed together to obtain a liquid crystal/organic solvent two-phase system. The liquid crystal is preferably fixed on a porous support, in particular a glass support. The reaction is carried out in a flow-through reactor which contains the liquid crystal in the abovementioned form or in thin layers adjacent to narrow flow channels, the borders of which are liquid permeable and through which the substrate-containing solvent is passed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9312072-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE35230-E
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101827810-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5350871-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8471053-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5714356-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5346816-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5177242-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010261929-A1 |
| priorityDate |
1990-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |