http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5112832-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5deddb47ccaab1d4da2aacc344dd8717 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-14 |
| filingDate | 1990-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1992-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84c52c76da2649a0e1b84da579505ca3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e7347735936f3ded44cf160f8132248 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_880ad195686b9fede375c1c9acb2baf3 |
| publicationDate | 1992-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5112832-A |
| titleOfInvention | Certain cyclopenta[b]pyridines and 5,6,7,8-tetrahydroquinolines having anti-inflammatory activity |
| abstract | The invention concerns compounds of formula I ##STR1## or a salt thereof, wherein R 1 and R 2 each independently represent hydrogen, lower alkyl, lower alkoxy, carboxyloweralkyl, carboxy, hydroxyloweralkyl, halogen, haloloweralkyl, lower alkoxycarbonyl, optionally substituted aryl or optionally substituted aralkyl, n represents an integer from 3 to 6; R 3 represents hydrogen or single or multiple substitution on one or more of the aliphatic carbons by one or more substituents selected from lower alkyl, optionally substituted aryl and optionally substituted aralkyl; A represents a group of formula (i) or (ii) below: n n --CR.sup.4 R.sup.5 --(CR.sup.6 R.sup.7).sub.m -- (i) n n n --CX--(CR.sup.6 R.sup.7).sub.m -- (ii) n n in which R 4 , R 6 and R 7 each independently represent hydrogen or lower alkyl (providing that when R 5 is NH 2 , R 0 is hydrogen); m is 0 or 1; R 5 represents hydrogen, NH 2 , OH or loweralkoxy, and X is ═O, ═NH or ═NOH, the attachment of A to B being from either end, and B represents an optionally substituted aryl or heteroaryl radical which compounds possess anti-inflammatory activity. Also disclosed is a process for preparing a useful intermediate to compounds of formula I. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5604238-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6103738-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5593943-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2004281959-B9 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2004281959-B2 |
| priorityDate | 1988-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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