| abstract |
Compounds of formula ##STR1## wherein R 1 is hydrogen or one or more specified substituents, n X is --O-- or --NR 2 -- where R 2 is lower alkyl, lower alkenyl, lower alkynyl, aryl or specified substituted lower alkyl or R 2 represents a group --Z-- which is connected to the 8-position of the aromatic ring so as to form a heterocyclic ring of 5 to 7 ring members, n Y is O or NR 3 where R 3 is hydrogen or lower alkyl, and n B is a saturated azabicyclic ring (eg tropanyl or quinuclidinyl) or a N-oxide thereof and their acid addition salts are 5-HT 3 antagonists which may be used in, for example, the treatment of neuro-psychiatric disorders. |