Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba4f31bd107def9877e9c7c9231cdc8e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2123-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F13-005 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 |
filingDate |
1988-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1992-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62a60a478af1aea7383b8d34d840de19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d87577fbada9a184bee746549eaf2f42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98dbb7f4d3721f2cecb4e52305fd60a6 |
publicationDate |
1992-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5081232-A |
titleOfInvention |
Complexes of tc99m radiopharmaceuticals |
abstract |
Complexes useful as radiopharmaceuticals contain the <99m>Tc-NO moiety and a ligand which confers biological target-seeking properties on the complex. Preferred are mono-cationic complexes, particularly having the formula [<99m>Tc(NO)L2X]<+> where X is halide or pseudohalide and L is a bidentate ligand for Technetium, which have interesting properties for use as heart visualising agents. Examples of ligands include di-(dialkyl and diphenyl)-phosphinoethanes and o-phenylenebisdimethylarsine. The complexes may be made by reacting generator eluate pertechnetate with a hydroxylamine salt and with the ligands, preferably in a single step by providing a reaction mixture containing the three reagents optionally in the presence of a reducing agent. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6329513-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5961952-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6124440-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6515112-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6001979-A |
priorityDate |
1987-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |