http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5073550-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-20 |
| filingDate | 1990-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1991-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_037e59f9554c70ff97c56559eee6d3ba |
| publicationDate | 1991-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5073550-A |
| titleOfInvention | Cephalosphorins with sulfur-containing oxyimino side chain |
| abstract | Antibacterial compounds of the formula <IMAGE> I wherein R is a mononuclear carbocyclic aromatic group, a 5-membered aromatic heterocyclic group which contains as the hetero (non-carbon) ring member(s) an oxygen or sulphur atom or an imino or lower alkylimino group and, optionally, one or two nitrogen atoms, or a 6-membered aromatic heterocyclic group which contains one to three nitrogen atoms as the hetero ring member(s); R1 is hydrogen or a 3-substituent which is usable in cephalosporin chemistry; A is lower alkylene or C3-7cycloalkylene which is optionally substituted with carboxy, carbamoyl, lower alkylcarbamoyl or di-(lower alkyl)carbamoyl; Q is lower alkylene or C3-7cycloalkylene which is optionally substituted with carboxy, carbamoyl, lower alkylcarbamoyl or di(lower alkyl)carbamoyl, or the group -NR2- or -NR2NR3-; R2 and R3 are independently hydrogen or lower alkyl; p and m are the zero or 1, n is zero, 1 or 2; R4 is hydrogen, lower alkanoyl or tri(lower alkyl)silyl; two R4 groups together represent diphenylmethylene; R5 is hydrogen, lower alkyl, hydroxy, lower alkoxy, halogen, nitro, -OCOR7, -OCOOR71, -N(R7)2, -NHCOR7, -NHCOOR71, -COR7, -SR7, -SOR7, -SO2R7, -SO3H, -COOR7 or -CON(R7)2R6 is hydrogen, lower alkyl or halogen, R7 is hydrogen or lower alkyl; R71 is lower alkyl, and the two -OR4 groups are attached to the phenyl ring via adjacent carbon atoms, as well as readily hydrolyzable esters and pharmaceutically acceptable salts of these compounds and hydrates of compounds of formula I and of their esters and salts. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8685957-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10028963-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8968753-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9872906-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10420841-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9320740-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8476425-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10933053-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8809314-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9724353-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10376496-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9044485-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9925196-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8906898-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11278622-B2 |
| priorityDate | 1987-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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