Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97ddd4d1d0ebc8a7d2c8e7d214d08cf3 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-277 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-34 |
filingDate |
1989-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1991-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e301b54cbaf2979674b46b75fe96af3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c589a1d277bd394258e4910e7b44a09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87b32684b8669b538912c96f2045025c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_982e9dfa54c2e047cecd71172130bc1e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44fb04f4b9c6d31d767ec452a5f52d5c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c06e45bb4197af7c49919b1d46a1d85 |
publicationDate |
1991-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5063243-A |
titleOfInvention |
Derivative of caffeic acid and pharmaceutical composition containing the same |
abstract |
Novel derivatives of caffeic acid of the general formula (I): <CHEM> wherein X is hydrogen atom or hydroxy; R<1> is hydrogen atom, a straight or branched alkyl or alkenyl having 1 to 20 carbon atoms or a group of the formula: -(CH2)n-Z-R<2> wherein n is an integer of 1 to 10; Z is oxygen atom, vinylene residue or a single bond; and R<2> is a substituted or unsubstituted phenyl or heterocyclic residue is provided. These derivatives possess 12-lipoxygenase inhibitory activity and are useful for curing and preventing circulatory diseases. A pharmaceutical composition containing said derivative is also provided. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6699463-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6602515-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5514711-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004057911-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10214476-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5981569-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6831191-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6936735-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015274633-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5283352-A |
priorityDate |
1988-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |