abstract |
A method of inhibiting bone demineralization comprising administration of an effective amount of a compound having the formula ##STR1## where X is CH or N; n Y is O or S; n R 1 is 2-propenyl, C 1 -C 3 alkyl, benzyl or substituted benzyl where the substitutents are one or two of the same or different and are selected from methyl, ethyl, methoxy, ethoxy, hydroxy, chloro, bromo, or fluoro; n R 2 is C 2 -C 3 alkyl, allyl or cyclopropylmethyl; n R 3 and R 4 are both hydrogen or combine to form a carbon-carbon bond; and pharmaceutically acceptable acid addition salts thereof to a mammal requiring bone demineralization inhibition. |