http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5057505-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79751aeaa9923745648e5ae7d9c35782 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6539 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6539 |
| filingDate | 1989-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1991-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_376a359d3223a46d9d78240ac51a9dfe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cd5588efc1f3c4b0996401c68435c8b |
| publicationDate | 1991-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5057505-A |
| titleOfInvention | Substituted aminomethanediphosphonic acids and use in medicaments |
| abstract | Heteroarylaminomethanediphosphonic acids of the formula <IMAGE> (I) in which R1 represents an optionally benzo- or cyclohexeno-fused 5-membered heteroaryl radical that contains, as hetero atom(s), either from 2 to 4 N-atoms or 1 or 2 N-atoms as well as 1 O-atom or S-atom and that is unsubstituted or is substituted by lower alkyl; by phenyl that is unsubstituted or is substituted by lower alkyl, lower alkoxy and/or by halogen; by lower alkoxy; by hydroxy; by di-lower alkylamino; by lower alkylthio and/or by halogen; and R2 represents hydrogen or lower alkyl, and their salts, have a regulatory action on the calcium metabolism and can be used as active ingredients in medicaments for the treatment of illnesses that can be attributed to disorders of the calcium metabolism. They are manufactured, for example, as follows: in a compound of the formula <IMAGE> (II) in which X1 represents a functionally modified phosphono group X and X2 represents phosphono or similarly represents a functionally modified phosphono group X, the group(s) X is(are) converted into free phosphono. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5441945-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9949992-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010144679-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6057306-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5344825-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9867838-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6255288-B1 |
| priorityDate | 1986-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 352.