http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5053408-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b9036c33bbe3f4ea428655b76200f7c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
| filingDate | 1990-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1991-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c14b853fa8b8469d1ee8f759eeae449 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac40725a6d027c8f60cae8e0adf27505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7075e27f4f24c3e6a3a10817e3cab0da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f02022e7347cac19e678ea734d0991eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04e2e98ca009cdabe56e51774345e141 |
| publicationDate | 1991-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5053408-A |
| titleOfInvention | Hexitol derivatives having vasodilative activity |
| abstract | Disclosed are hexitol derivatives represented by the general formula (I): <CHEM> wherein Q represents a formula <CHEM> wherein a represents NH, O or S, each of b, c and d independently represents CH or N, each of R<1>, R<2>, R<3> and R<4> independently represents hydrogen, lower alkyl, trifluoromethyl, aryl, lower alkanoyloxy, amino, lower alkylamino, lower alkanoylamino, lower alkanoyl, aroyl, halogen, nitro, (CH2)mOR<7>, (CH2)mSR<7>, (CH2)mCO2R<7> where R<7> represents hydrogen or lower alkyl and m represents an integer of 0 to 3, each of R<5> and R<6> independently represents hydrogen or lower alkyl, <CHEM> wherein each of Y<1> and Y<2> independently represents hydrogen, lower alkyl, hydroxyl, lower alkanoyloxy, nitrile or phenyl; or Y<1> and Y<2> are combined together to form oxygen, each of Y<3> and Y<4> independently represents hydrogen or lower alkyl, and l is an integer of 0 to 6, and where l is an integer of 2 to 6, each <CHEM> may be the same or different, Z represents hydrogen or nitro, and, n is 2 or 3 or a pharmaceutically acceptable salt thereof. The compounds show prominent coronary vasodilative activities, and are useful in treating angina pectoris and myocardial infarction. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5120737-A |
| priorityDate | 1989-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 679.