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filingDate 1990-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1991-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1c01524d5315142c35e8d11263faaeb
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publicationDate 1991-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5047413-A
titleOfInvention Pharmaceutical compositions containing acylated benzilic acid derivatives
abstract Certain acylated benzilic acid derivatives are useful for influencing therapeutically the tone of the urinary bladder in humans and animals. These derivatives are N-alkyl-4-piperidyl α,α-diphenyl-α-acyloxyacetates having the formula ##STR1## wherein R is H, CH 3 , C 2 H 5 or C 3 H 7 ; R' is H, NH 2 , phenyl, carboxyphenyl, (C 1 -C 6 )alkyl, hydroxy(C 1 -C 6 )alkyl, methoxy, ethoxy, methoxymethyl, ethoxymethyl, amino(C 1 -C 6 )alkyl which can be substituted in the alkyl radical by one or more of a --NH 2 , --COOH or --SCH 3 group, N-acetylamino(C 1 -C 6 )alkyl, or a group having the formula n n --CH═CH--COOR" n n or n n --(CH.sub.2).sub.n --COOR" n n where n is an integer from 0 to 8, and R" is H, CH 3 , C 2 H 5 , C 3 H 7 , or a pharmacologically acceptable cation; or a salt thereof with a pharmaceutically acceptable acid.
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priorityDate 1987-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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