http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5047399-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7f82940e47ba7a1188f8e2ffca55e0f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0207 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0804 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-083 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02 |
| filingDate | 1988-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1991-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb3704a37c99b01e5abdb63e3f313954 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd7b4f240887b2003a7ad4e401868dc6 |
| publicationDate | 1991-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5047399-A |
| titleOfInvention | Hydrophobic pseudo-peptides |
| abstract | Novel hydrophobic psuedo-peptides of formula I <IMAGE> I wherein R1 is lower alkyl or -CH2 CONR6R7; R2, R3, R4 and R5 are independently lower alkyl, cycloalkyl lower alkyl, aryl lower alkyl, heteroaryl lower alkyl, aryl lower alkoxy, substituted aryl lower alkyl, wherein the aryl portion is substituted with 1-3 substituents independently selected from lowr alkyl, hydroxyl, lower alkoxy and halogeno, substituted heteroaryl lower alkyl wherein the substituents on the heteroaryl portion are as defined for aryl lower alkyl, substituted cycloalkyl lower alkyl, wherein the substituents on the cycloalkyl portion are as defined for aryl lower alkyl, and substituted aryl lower alkoxy wherein the substituents are as defined for aryl lower alkyl; R6 and R7 are independently hydrogen or lower alkyl; X1, X2, X3, X4 and X5 are independently <IMAGE> cis or trans -CR8=CR9-, -CHR8CHR9-, -CH2NR8-, <IMAGE> provided that when R4 is methyl, X4 is not -CONH-; R8 and R9 are independently hydrogen or lower alkyl; the pharmaceutically acceptable salts thereof,a nd pharmaceutical compositions thereof, useful in the treatment of hypertension are disclosed. |
| priorityDate | 1988-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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