http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5037975-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D463-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-085 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D463-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-085 |
filingDate | 1990-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1991-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f9ee8114ee876108393bd30f88c1aa7 |
publicationDate | 1991-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-5037975-A |
titleOfInvention | Cephalosporin free radical compounds |
abstract | The invention provides a free radical process for preparing 1-carba(1-dethia)cephalosporin antibiotics with 2-substituted methylcephalosporin 1,1-dioxides wherein the substituent on the 2-methylene group is a free radical precursor group such as a phenyl or alkylseleno group. The latter dioxides are treated with a free radical initiator, e.g., a trialkyltin hydride or actinic radiation at 40 DEG C. to 150 DEG C. to provide the 1-carba-3-cephem and 1-carba-2-cephem products. The invention also provides free radical compounds formed as intermediates in the process. |
priorityDate | 1988-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 313.