| abstract |
The invention refers to new diamines of the Formula I ##STR1## wherein R stands for ##STR2## or --NH--COA 1 --R 4 or ##STR3## wherein A stands for C 1-5 alkylene which can be substituted by hydroxyl, n X stands for a single or double bond, n R 2 stands for aryl or heteroaryl optionally substituted by halogen, C 1-4 alkoxy or acylamino, n R 3 stands for hydrogen or C 1-4 alkyl, n A 1 stands for a single bond or C 1-5 alkyl optionally substituted by hydroxyl or thioalkylene or oxyalkylene, n R 4 stands for a 5- or 6- membered aromatic or heteroaromatic ring which can be substituted by one or more hydroxyl, C 1-4 alkyl and/or C 1-4 alkoxy and/or halogen or methylenedioxy and the alkyl group can be unsaturated as well, n Q stands for a 6-membered ring which can be partially hydrogenated, and n R 1 stands for C 1-4 alkyl. n The new compounds are antiarrhythmic agents. |