| abstract |
The present invention relates to the derivatives of the formula <IMAGE> formula (I) in which: A is an aromatic ring or a nitrogen heterocycle; X1, X2, X3 and X4 are independently a hydrogen atom, a halogen atom, a lower alkyl radical, an alkoxy radical, an alkylthio radical, a sulfone group, a sulfoxide group, a trifluoromethyl group, a nitro group, a hydroxyl group, a methylene alcohol radical or a group COOR', in which R' is a hydrogen or a lower alkyl; X3 and X4 can also form a naphthalene with the phenyl; B is CR5R6, R5 and R6 being a hydrogen atom or a lower alkyl, or the sulfur atom; R1, R2, R3 and R4 are independently a hydrogen atom or a lower alkyl radical; CR1R2 or CR3R4 can form with B, when the latter is CR5R6, a cycloalkyl or a cycloalkene having 3 to 7 carbon atoms; R1R2 and R3R4 can also form a ring having 3 to 6 carbon atoms; n is an integer from 1 to 4 and can be 0 if R1 and R2 are other than hydrogen; and D is a chemical group which can be: COOR7, R7 being the hydrogen atom or a lower alkyl, CONH-R8, R8 being the hydrogen atom or a lower alkyl, CN, <IMAGE> R9 being the hydrogen atom or a lower alkyl, or NHSO2CF3, and to their addition salts. |