abstract |
A 3(2H)pyridazinone of the formula: ##STR1## wherein R 1 is hydrogen, 2-propenyl, or straight chained or branched C 1 -C 4 alkyl; each of R 2 and R 3 which may be the same or different, is hydrogen, or straight chained or branched C 1 -C 3 alkyl; X is chlorine, or bromine; Y is hydrogen, halogen, nitro, amino, or --AR 4 wherein A is oxygen, or sulfur, and R 4 is hydroen, straight chained, branched or cyclic C 1 -C 8 alkyl, ##STR2## wherein R 5 is hydrogen, or straight chained or branched C 1 -C 4 alkyl; and Ar is ##STR3## wherein each Z 1 and Z 2 which may be the same or different, is hydrogen, halogen, straight or branched C 1 -C 4 alkyl, or --OR 6 wherein R 6 is straight or branched C 1 -C 4 alkyl, and B is oxygen, sulfur, or --N═C-- (to form a quinoline or pyridine ring); or a pharamaceutically acceptable salt thereof. |