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publicationDate 1991-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5008377-A
titleOfInvention Production of proteins in active forms
abstract For the preparation of a protein in a physiologically active or native form, a source of protein in a solubilised form is contacted with cationic exchange medium which may be a cationic exchange resin which generates a rapid ion exchange rate. The cationic exchange resin may be provided in the form of a cationic exchange chromatography column, the source of protein being contacted therewith via elution of the chromatography column. The protein is then recovered in a physiologically active form. This represents a highly efficient, and hence cost effective, method for the recovery of proteins.
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