http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5008293-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_824365c898d616e4b3df1330cfd071bb |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-085 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-085 |
filingDate | 1988-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1991-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c093b03309966ff52f4ac48511daad8 |
publicationDate | 1991-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-5008293-A |
titleOfInvention | Process for the treatment of the skin to alleviate skin diseases arising from contact sensitization or irritation utilizing p-substituted phenoxy alkanols |
abstract | Skin diseases are treated by topical application of p-substituted phenoxy alkanols having the structure: <IMAGE> (I) in which: R1 substituted in ortho, meta or para position is selected from hydrogen, halogen, alkyl having from one to six carbon atoms, preferably para-chlorine or para-tertiary-butyl; and bivalent cycloalkylene condensed with the phenyl group at adjacent ring carbons thereof, such as in indane; R2 and R3 are hydrogen or hydroxyl and at least one of R2 and R3 is hydroxyl; and N1, n2 and n3 represent the number of CH2, CHR2 and CH2 groups, respectively, and are numbers within the range from 1 to 10. The topical application to the skin of these compounds jointly with an agent that causes irritation, inflammation or contact sensitization modifies and mitigates such irritation, inflammation and sensitization. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8586066-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5183901-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2001520184-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5958379-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003125347-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009149473-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8623412-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006104909-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8026238-B2 |
priorityDate | 1988-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 145.