| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6ede6dfd510f800f051b3578956a2999 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 |
| filingDate |
1990-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1991-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b683eeb8bb44d7163abb44c345b6d8d |
| publicationDate |
1991-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4999369-A |
| titleOfInvention |
Tetracyclic heterocyclic derivatives, pharmaceutical compositions and use |
| abstract |
The present invention relates to compounds of the formula (I) ArCH2NHR<1> (I) or a monomethyl or monoethyl ether thereof, the compound of formula (I) including the said ethers containing no more than 29 carbon atoms in total; an ester thereof; a salt thereof; wherein Ar is a ring system of formula <CHEM> wherein <CHEM> is a five-membered ring containing at least one heteroatom and two double bonds or a substituted derivative thereof or a resonance form thereof, the heteratom is preferably oxygen, sulphur or nitrogen substituted by hydrogen methyl or ethyl; R<1> contains not more than eight carbon atoms and is a group <CHEM> wherein m is 0 or 1; R<5> and R<6> are the same or different and each is hydrogen or C1-3 alkyl optionally substituted by hydroxy; R<7> and R<8> are the same or different and each is hydrogen or C1-3 alkyl; -C-C is a five-or six-membered saturated carbocyclic ring; R<9> is hydrogen, methyl or hydroxymethyl; R<1><0>, R<1><1> and R<1><2> are the same or different and each is hydrogen or methyl; R<1><3> is hydrogen, methyl, hydroxy or hydroxymethyl. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9956226-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014124412-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004092543-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6992100-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-692563-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9761808-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5721267-A |
| priorityDate |
1986-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |