http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4992424-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23K20-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-90 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23K20-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-10 |
filingDate | 1989-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1991-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0f8b747a4ffb639df2410d76731dea4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_790a05de9c7006564c93afe1fa58a1e2 |
publicationDate | 1991-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-4992424-A |
titleOfInvention | Antiparasitic avermectin derivatives |
abstract | Compounds of the formula: <CHEM> wherein the broken line at the 22-23 position represents an optional double bond and wherein either R<1> is H or OH and the double bond is absent, or, the double bond is present and R<1> is absent; R<2> is =CH2 or a group of the formula -(X)-C(R<5>)=CHR<6>; R<3> is H or CH3: R<5> and R<6> are both H; R<5> is H and R<6> is C1-C3 alkyl; or one of R<5> and R<6> is H and the other is phenyl, heteroaryl, C2-C6 alkoxycarbonyl or substituted phenyl or heteroaryl wherein said substituent is fluorine, chlorine, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 alkylthio, hydroxy(C1-C4)alkyl, cyano, aminosulphonyl, C2-C6 alkanoyl, C2-C6 alkoxycarbonyl, nitro, trifluoromethyl, trifluoromethoxy, amino or mono or di-C1-C4 alkylamino; and X is a direct bond or is an alkylene group having from 2 to 6 carbon atoms which may be straight or branched-chain; with the proviso that R<5> and R<6> are not both hydrogen when X is -CH(CH3)CH2-, are broad spectrum antiparasitic agents having utility as anthelmintics, ectoparasiticides, insecticides, acaricides and animal growth promotants. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5376678-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5556868-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5665708-A |
priorityDate | 1988-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 90.