http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4988708-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4acae202b6a15394281949545e70d2f6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D265-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D265-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-75 |
| filingDate | 1988-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1991-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30fae5dc88be4f3089d5571357a75c0b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee70db1d5557ced78299439cc0b4695a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_019039578c94a0e8710e2b7bcaac186f |
| publicationDate | 1991-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4988708-A |
| titleOfInvention | Analgesic and anti-inflammatory 4-OH quinoline carboxylic acid derivatives |
| abstract | A compound selected from the group consisting of optical isomers and racemates of 4-hydroxy-3-quinoline carboxylates of the formula ##STR1## wherein X is in the 5-, 6-, 7- or 8-position and is selected from the group consisting of hydrogen, halogen, alkyl of 1 to 5 carbon atoms, alkoxy of 1 to 4 carbon atoms, --CF 3 , --SCF 3 , and OCF 3 , R 1 is selected from the group consisting of hydrogen and alkyl of 1 to 4 carbon atoms, R 2 is selected from the group consisting of thiazolyl, 4,5-dihydrothiazolyl, pyridinyl, oxazolyl, isoxazolyl, imidazolyl, pyrimidyl and tetrazolyl, all optionally substituted with alkyl of 1 to 4 carbon atoms and phenyl and phenyl substituted with at least one member of the group consisting of --OH, alkyl and alkoxy of 1 to 4 carbon atoms, --CF 3 , --NO 2 and halogen, A is ##STR2## in which R 3 and R 4 are individually selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms and aryl, R 5 is heteroaryl f 3 to 14 carbon atoms optionally substituted with alkyl of 1 to 4 carbon atoms and their non-toxic, pharmaceutically acceptable salts with acids or bases having analgesic and anti-inflammatory activity. |
| priorityDate | 1984-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 295.