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publicationDate 1990-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-4968616-A
titleOfInvention Superoxide dismutase derivatives, method of producing same and medicinal use of same
abstract Novel superoxide dismutase derivatives are provided in which the enzymatic activity of superoxide dismutase capable of decomposing superoxide, a substance harmful to living organisms, is for the most part maintained with the plasma half-life being significantly prolonged as compared with superoxide dismutase itself. They have pharmacological activities such as anti-inflammatory, anti-ischemic and cerebral edema-preventing activities. Also provided are a method of producing such superoxide dismutase derivatives and medicinal uses of them.
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