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filingDate 1989-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74aaf4bf1e77c3b638bfd156d40fe4a2
publicationDate 1990-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-4956466-A
titleOfInvention Thiazole derivatives and process for the preparation thereof
abstract Thiazole derivatives of the general formula where: ##STR1## X is an anion of pharmaceutically acceptable acids; a is an integer from 1 to 5; n b is an integer from 1 to 7; n c is 0 or an integer from 1 to 4; and n d is 2a-c for monovalent acid anions, is a-c for divalent acid anions, and is 0 or 2 when c=0. n The process for the preparation of the above derivatives is based on reacting N-methyl-N'-2-((2-(dimethylaminomethyl)-4-thiazolyl) methylthio)ethyl)-2-nitro-1,1-ethylenediamine of formula II with an X anion containing zinc compound or an organozinc.
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