| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_00c9d781df3d4457e18aaf9b2ca26d06 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 |
| filingDate |
1988-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1990-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc1d9421d0f025e7de8ff4c9dcb5e7bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_807c173f77bb2d7383424e8919e3c68f |
| publicationDate |
1990-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4950770-A |
| titleOfInvention |
Psoralens aminomethylation |
| abstract |
A direct, acid-catalyzed substitution reaction incorporates an N-phthalimidomethyl group on the 4' or 5' carbon of a psoralen in yields of 60-80% via the condensation of an N-hydroxymethylamide or phthalimide (e.g. N-hydroxymethylphthalimide) and an appropriately substituted psoralen. The phthalimide moiety is cleaved from the psoralen ring by treatment with hydrazine to give 60 to 70% yields of the aminomethylpsoralens. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007073028-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6503699-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0707476-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0707476-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009155224-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6255324-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6686480-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8071642-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6177424-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7238768-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004210074-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5356929-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5216176-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003114854-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6469052-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5473083-A |
| priorityDate |
1987-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |