abstract |
4(R)-Substituted 6(S)-phenyloxymethyl-, 6(S)- beta -phenylethyl- and 6(S)- beta -styryl-tetrahydropyran-2-ones of the general formula V <IMAGE> V in which R7, R8 and A have the meanings given, and the corresponding open-chain hydroxycarboxylic acids, pharmacologically acceptable salts and esters thereof, processes for the preparation of these compounds, their use as medicaments and pharmaceutical products are described. Novel alpha , beta -unsaturated lactones for the preparation of the compounds of the formula V are also described. |