| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_71c973d3447f2ef5c41cdbe910a41783 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4422
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-451
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-10 |
| filingDate |
1988-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1990-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79e8de71de2e5b6277e4ded076aaeb88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_571df2c8a1ca49dc6f1719bf1370d34b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e785895386f921ef19a05761b9e8b83b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78f0e28802af69bd4ff480b23f8cbd1b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cde289fec0e5d94fca0fb400c92ef2e3 |
| publicationDate |
1990-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4946851-A |
| titleOfInvention |
1.4-dihydropyridines |
| abstract |
Compounds are described of the formula <CHEM> wherein R1 and R4 independently represent a C1-4 alkyl group; R2 and R3 independently represent a C1-6 straight or brached alkyl chain or alkoxy group; R4 represents a C1-4 alkyl group; R5 represents a group CH=CR6R7 where R6 is a hydrogen atom or C1-3 alkyl group and R7 represents an aryl, pyridyl or cyano group; or R5 represents the group C IDENTICAL CR8 where R8 is an aryl group. The compounds represented by formula (1) reduce intracellular calcium ion concentration by limiting transmembranal calcium ion influx and thus may be useful for the treatment of cardiovascular disorders such as hypertension. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5362729-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008089947-A1 |
| priorityDate |
1986-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |